The employer will submit applications to the US Department of Labor and US Citizenship and Immigration Services (USCIS0. This is done in order to demonstrate that the employer, position and employee meet the criteria for the H-1B status.

If the employee is in the US, a change of status from F-1 to H-1B within the US may be obtainable. 

If the employee is outside the US, the employee applies for an H-1B visa at a US consulate and enters the states with a H-1B status